comm-acq pneumonie - S.aureus (non-MRSA)
Advices
| Priority | Medication | Remarks | 
|---|---|---|
| 
                                              Medication: flucloxacilline po 500mg 4dd or 
                                                                            clindamycine po 600mg 3dd or 
                                                                            cotrimoxazol (trimethoprim +sulfamethoxazol) po 960mg 2dd  | 
                    
                                               
                          Remarks: 
                           
                                          SWAB remarks oraal  | 
                  |
| 
                                              Medication: flucloxacilline iv 1000mg 4dd or 
                                                                            flucloxacilline iv loading dose 1000mg, 6000mg continuous per 24 hours or 
                                                                            cefazoline iv 1000mg 3dd  | 
                    
                                               
                          Remarks: 
                           
                                          SWAB remarks intraveneus  | 
                  
| Priority | Medication | Remarks | 
|---|---|---|
| 
                                              Medication: Vancomycine iv loading dose 30mg/kg, 17.5mg/kg 2dd  | 
                    ||
| 
                                              Medication: Vancomycine iv loading dose 20mg/kg, 35mg/kg continuous per 24 hours + 
                                                                            aminoglycoside iv 1dd  | 
                    ||
| 
                                              Medication: Vancomycine iv loading dose 20mg/kg, 35mg/kg continuous per 24 hours + 
                                                                            rifampicine iv 600mg 2dd  | 
                    
Sources
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
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Metadata
            Swab vid: G-7561.5
            Updated: 08/22/2024 - 13:07
            Status: Published
          
          
General comments
vancomycine dosering: oplaaddosis 20 mg/kg, vervolgens 35 mg/kg continu per 24 uur, OF oplaaddosis 30 mg/kg, vervolgens 17,5 mg/kg 2 dd. Onderhoudsdosering vancomycine verder afhankelijk van nierfunctie en van gemeten spiegels, zie bij vancomycine en bij TDM vancomycine
In CWZ:
flucloxacilline 1000 mg oplaaddosis gevolgd door 3000 mg 2 dd. gedurende 12 uur in continu infuus. bij ernstige infectie in combinatie met 3 dagen gentamicine (1 dd 3 mg/kg).